FIG. 4.

Optical images of acellular collagen hydrogel and TEML constructs after exposure to platelets. DiOC₆-labeled human platelet suspension was incubated with type I collagen hydrogel (A, B) or a TEML (C, D) for 15 min at 37°C with gentle agitation of samples. Platelet aggregation was recorded, after the samples were washed with HBS, under a brightfield microscope (A, C) and fluorescence microscope (B, D). Results presented are representative of four experiments. Scale bar = 50 μm. HBS, HEPES-buffered saline. Color images available online at www.liebertpub.com/tec