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. 2016 Jun 29;17(Suppl 3):438. doi: 10.1186/s12864-016-2786-z

Table 2.

Results from Fisher’s exact test. The odds ratios observed were higher for E318G+ individuals than E318G– individuals with the same number of APOEε4 alleles, but the 95 % confidence intervals for these groups overlap

Alzheimer’s risk based on E318G status and number of APOEε4 Alleles
Strata Cases Controls P value OR (95 % CI) Power
E318G + APOEε44 1 1 0.197 9.1 (0.1–759.3) 0.04
APOEε4 (+) 7 19 0.043 3.5 (1.0–12.7) 0.16
APOEε4 (−) 8 77
E318G – APOEε44 36 48 2.4 × 10−15 7.5 (4.6–12.0) 1.0
APOEε4 (+) 217 717 <2.2 × 10−16 3.0 (2.4–3.7) 1.0
APOEε4 (−) 209 2080