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. 2016 Jul 13;11(7):e0158967. doi: 10.1371/journal.pone.0158967

Fig 1. Expression of CHST15 mRNA during the shift from inflammation to fibrosis in mouse colitis.

Fig 1

(A) Schematic representation of acute and chronic DSS colitis. (B) Endoscopic and histological findings. Representative photos of immunostaining for F4/80 and ER-TR7 (brown) in mice of disease controls (without performing siRNA injection) at indicated times are shown. Original magnification, x200. (C) Kinetics of positive area (%) for ER-TR7 (dotted line) and F4/80 (black line) of disease control mice. (D) Kinetics of CHST15 mRNA expressions in the colon of disease control mice. Results are expressed as mean ± SD (n = 4~6). *p<0.05, **p<0.01 and ***p<0.001 vs. normal mice (day 0) by Student’s t-test. Representative data were shown from 3 independent experiments.