Table 5. Annual cost per patient by EDSS classification group and cost ratios.

First author, country	Year of cost	EDSS Classification			Annual cost per patient (USDPPP), recalculated at 2011 (1% inflation rate)			Cost ratio classification II vs. I	Cost ratio classification III vs. I
		I	II	III	I	II	III
Auty [33], Canada	1995	≤2.5	3–6	≥6.5	14 032	20 964	35 771	1.50	2.50
Dusankova [26], Czech Rep.	2007	0–3.5	4–6.5	7–9.5	12 512	17 765	28 902	1.42	2.31
Henriksson [35], Sweden	1998	≤3	3.5–6	≥6.5	18 966	36 818	92 861	1.94	4.90
Karampampa [38], Canada	2009	0–3	4–6.5	7–9	26 155	39 545	66 143	1.51	2.53
Karampampa [37], France	2009	0–3	4–6.5	7–9	19 041	34 792	52 320	1.83	3.75
Karampampa [40], Germany	2009	0–3	4–6.5	7–9	26 795	50 521	81 331	1.89	3.04
Karampampa [39], Spain	2009	0–3	4–6.5	7–9	29 819	63 433	85 660	2.13	2.87
Karampampa [42], UK	2009	0–3	4–6.5	7–9	18 485	40 424	92 135	2.19	4.98
Karampampa [41], Italy	2009	0–3	4–6.5	7–9	29 512	54 300	52 020	1.84	1.76
Karampampa [43], Netherlands	2011	0–3	4–6.5	7–9	37 199	61 388	120 801	1.65	3.25
Orlewska [57], Poland	2002	<3.5	4–6	>6.5	15 720	22 391	26 497	1.42	1.69
Palmer [58], Australia	2010	1–3	4–6	6.5–9	24 389	39 491	43 793	1.62	1.80
Mean (SD)					22 719	40 153	64 853	1.75 (0.26)	2.86 (1.09)