Table 6.
Overview of literature presenting clinical chemistry data from several mouse strains
| Mice |
||||||||
| Reference | Strain | Sex | Age | No. per group | Experimental conditions | Sample | Analytical device | Data |
| 7 | C57BL/6J | Male and female | 9–12 wk | 25–100 | Comparison of conditions (housing, fasting duration, diet, diurnal rhythm, anesthesia), retrobulbar collection | Heparin-treated plasma, fresh | AU400 (Olympus) | Mean ± SEM |
| 8 | C57BL/6J, 129SvPas, BALB/cByJ, C3HeB/FeJ | Male and female | 3, 6, and 12 mo | 40 | Overnight fasting values, isoflurane anesthesia, retrobulbar collection | Heparin-treated plasma, fresh | AU400 (Olympus) | Mean ± SEM |
| 18 | B6D2F1 | Male | ~45 d | 304 | Single housing, treatments before blood collection, chloroform anesthesia, thoracotomy, cardiocentesis | K2-EDTA plasma (fresh or frozen) | Basic microanalyzer (Ortho Instruments) | Percentiles, mean ± 1 SD |
| 19 | C3H, BALB/c | Male and female | 56–78 d | 18–26 | Samples collected from tail vein | Heparin-treated plasma, fresh | AU400 (Olympus) | Mean ± SEM |
| 23 | C3HeB/FeJ, C57BL/6JIco, BALB/c, C3BlF1, B6C3F1, C3CF1, CC3F1 | Male and female | 12 wk | 37–132 | Overnight fast, ether anesthesia, retrobulbar collection | Heparin-treated plasma, frozen | Hitachi 717 (Roche) and AU400 (Olympus) | Mean ± SEM |
| 27 | C57BL/6J, 129SV/EV, C3H/HeJ | Male and female | 2, 4, 6, 8, 10, and 12 mo | 15 | Isoflurane anesthesia, retrobulbar collection, analysis of pooled samples (3 mice) | Serum, frozen | Vitros 250 (Ortho Diagnostics) | Median and percentiles |
| 36 | FVB/NTac | Male and female | 7–9 wk | 52–54 | Microisolation housing, CO2 anesthesia, cardiocentesis | Serum, frozen | Vitros DTII (Ortho Diagnostics) | Percentiles, mean ± 1 SD |
| 38 | FVB/NCrlBR, C57BL/6J-Tyrc2J/+, Swiss Webster (outbred) | Male and female | 14–18 wk | 16–18 | Housing with cage enrichment, 4-h fasting, CO2 anesthesia, cardiocentesis | Serum, fresh | Hitachi 704 (Boehringer Mannheim) | Minimum, maximum, mean ± 1 SD |
| 42 | C3H/HeH, BALB/cAnNCr, C57BL/6J | Male and female | 24–30 wk | 10–20 | Single housing in metabolic cages for 7 d; sample collected from internal jugular vein after euthanasia | Heparin-treated plasma, frozen | AU400 (Olympus) | Mean ± 1 SD |