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Distance traveled and center time in a novel open field. Data are shown as the mean ± SEM for a 1-h test. (A and D) The results from B6 mice are included as examples of the typical activity and exploration of wild-type mice. (B) BALB/c and (C) 129/Sv male mice. (E) BALB/c and (F) 129/Sv female mice. Value differed significantly (P < 0.05) from the mean for (Λ) male B6 mice, (*) the nest-only group, or (#) both other enrichment conditions.
