Table 11.

Histological lesions (score; mean ± 1 SD) associated with CO₂euthanasia

	Chamber replacement rate (per minute)
	15% (n =14)	30% (n =14)	50% (n =18)	100% (n =14)	Pa
Perivascular edema	1.14 ± 0.86	1.14 ± 0.77	0.89 ± 0.90	0.79 ± 0.57	0.49
Congestion	0.14 ± 0.36	0 ± 0	0.17 ± 0.38	0.21 ± 0.42	0.38
Hemorrhage	0.29 ± 0.61	0.07 ± 0.26	0.06 ± 0.24	0.07 ± 0.26	0.42

Lesions were scored according to the following scale: 0, no lesion; 1, mild lesion; 2, moderate lesion; and 3, severe lesion

^aANOVA group significance level