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. 2016 Jul;55(4):451–461.

Table 6.

Cardiovascular values (mean ± 1 SD; n≥ 12 mice per group) for total AUC above baseline for time until death at various CO₂CRR

	Chamber replacement rate (per minute)
	15%	30%	50%	100%	P^b
Total heart rate (sum of heart beats)^a	10549 ± 5884	8569 ± 4060	4159 ± 1888	3354 ± 1892	<0.0001
Heart rate (beats per second)^a	51.7 ± 7.9	54.9 ± 26.0	41.8 ± 20.0	47.8 ± 27.0	0.23
Total systolic blood pressure (sum of mm Hg)^a	1862 ± 1280	1816 ± 706	1315 ± 702	845 ± 319	0.13
Systolic blood pressure (mm Hg) per second	9.0 ± 6.0	11.7 ± 5.2	12.7 ± 5.4	11.9 ± 4.4	0.24
Total diastolic blood pressure (sum of mm Hg)^a	2082 ± 1527	2091 ± 1023	1481 ± 859	931 ± 374	0.02
Diastolic blood pressure (mm Hg) per second	10.0 ± 6.9	13.5 ± 7.2	14.2 ± 7.1	13.13 ± 5.11	0.51
Total mean blood pressure (sum of mm Hg)	1891 ± 1339	1874 ± 832	1316 ± 741	851 ± 339	0.08
Mean blood pressure (mm Hg) per second	9.1 ± 6.1	12.1 ± 5.9	12.7 ± 5.9	12.0 ± 4.6	0.27

^a

Data were transformed for analysis

^b

ANOVA group significance level