Table 4.

Plasma NGAL for the prediction of acute kidney injury after pediatric cardiac surgery.

Reference	Sample size	AKI events	AKI definition	Timing (hours)	AUC	Cut-off (ng/ml)
Mishra [66]	71	20	≥50% increase in SCr	2 h	0.90	50
Dent [76]	120	45	≥50% increase in SCr	2 h	0.96	150
Krawczeski [47]	374	112	≥50% increase in SCr	2 h	0.94	45
Parikh [70]	311	53	≥100% increase in SCr	<6 h	0.56	260
Fadel [77]	40	32	≥50% increase in SCr	2 h	0.95	100
Total	916	262			0.86

SCr, serum creatinine; timing refers to hours since starting cardiopulmonary bypass when the plasma sample was obtained.