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. 2015 Dec 22;15(3):455–470. doi: 10.1080/15384101.2015.1127478

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Figure 8. — ARTIK-52 treatment induces DNA damage in sensitive, but not resistant cells. A, B. Immunofluorescent staining of ARTIK-52 sensitive, CWR22R (A) or resistant, Hela (B) cells treated with 1 μM of ARTIK-52 or 1 μg/ml of etoposide for 6 hours with γH2AX antibody and Hoechst 33342 DNA stain. C. Comet assay in alkali conditions with cells treated with 1 μM of ARTIK-52 or 1 μg/ml of etoposide for 16 hours. D. PFGE of DNA from cells treated with 1 μM of ARTIK-52 or 1 μg/ml of doxorubicin for 16 hours.