Table 17. Salivary proteins shared by New and Old world sand flies.
| Family of proteins | B. olmeca | Lu. longipalpis | Lu. ayacuyensis | N. intermedia | Phlebotomus |
|---|---|---|---|---|---|
| Proteins specific to New World sand flies | |||||
| Toxins family | ☑ | - | - | ☑ | - |
| RGD-containing | ☑ | ☑ | ☑ | ☑ | - |
| C-type lectin | ☑ | ☑ | ☑ | ☑ | - |
| Maxadilan peptide | - | ☑ | - | ☑ | - |
| 14kDa | ☑ | ☑ | - | ☑ | - |
| ML domain peptide | ☑ | - | - | ☑ | - |
| 5’ Nucleotidase | - | ☑ | - | - | - |
| 10 kDa family | ☑ | ☑ | - | ☑ | - |
| 11.5 kDa protein | ☑ | ☑ | ☑ | - | - |
| 71 kDa proteins | ☑ | ☑ | - | - | - |
| Molecules or Proteins specific to Old World sand flies | |||||
| Adenosine | - | - | - | - | ☑ |
| Glutathione 5 transferase | - | - | - | - | ☑ |
| Pyrophosphatase | - | - | - | - | ☑ |
| Phospholipase A2 | - | - | - | - | ☑ |
| 12kDa protein of unknown function | - | - | - | - | ☑ |
| 3kDa protein of unknown function | - | - | - | - | ☑ |
| 27kDa protein of unknown function | - | - | - | - | ☑ |
| Proteins common to Lutzomyia and Phlebotomus sand flies | |||||
| Small Odorant Binding Proteins | ☑ | ☑ | ☑ | ☑ | ☑ |
| Yellow proteins | ☑ | ☑ | ☑ | ☑ | ☑ |
| Antigen 5 related proteins | ☑ | ☑ | ☑ | ☑ | ☑ |
| Lufaxin | ☑ | ☑ | ☑ | ☑ | ☑ |
| Large OBP/D7- related proteins | ☑ | ☑ | ☑ | ☑ | |
| Apyrase | ☑ | ☑ | ☑ | ☑ | ☑ |
| Endonuclease | ☑ | ☑ | ☑ | ☑ | ☑ |
| hyaluronidase | ☑ | ☑ | - | ☑ | ☑ |
| Silk related/collagen binding proteins | ☑ | ☑ | ☑ | - | ☑ |
| Adenosine deaminase | ☑ | ☑ | - | - | ☑ |
| 56.6kDa proteins | ☑ | ☑ | - | - | ☑ |
| 38.8kDa proteins | ☑ | - | - | - | ☑ |
(☑) Protein or function described
(-) protein or function not described