Table 2. Analysis of factors associated with death.
n | Events (n) | Censored patients n (%) | Median survival (months) | 95%CI |
Log-rank p | ||
---|---|---|---|---|---|---|---|
Lower limit | Upper limit | ||||||
Level of carbohydrate antigen 19-9 | |||||||
<59 x ULN | 13 | 11 | 2 (15.4) | 17.5 | 7.2 | 27.8 | 0.212 |
≥59 x ULN | 10 | 9 | 1 (10.0) | 6.8 | 1.1 | 12.5 | |
Normal | 10 | 8 | 2 (20.0) | 13.3 | 6.1 | 20.4 | |
Pancreatic tumor site | |||||||
Head | 19 | 15 | 4 (21.1) | 15.6 | 6.1 | 25.0 | 0.482 |
Body | 6 | 5 | 1 (16.7) | 7.6 | 0.0 | 22.1 | |
Tail | 8 | 8 | 0 | 10.2 | 9.2 | 11.3 | |
First treatment | |||||||
Surgery | 2 | 2 | 0 | 7.6 | -- | -- | 0.337 |
Chemotherapy | 30 | 25 | 5 (16.7) | 15.6 | 4.0 | 27.1 | |
Chemo + radiotherapy | 1 | 1 | 0 | 9.6 | -- | -- | |
Site of metastasis | |||||||
Liver | 20 | 18 | 2 (10) | 10.2 | 7.2 | 13.2 | 0.197 |
Other | 13 | 10 | 3 (23.1) | 15.6 | 6.1 | 25.0 | |
Lymphovascular invasion | |||||||
Yes | 2 | 2 | 0 | 7.6 | -- | -- | 0.286 |
No | 31 | 26 | 5 (16.1) | 15.6 | 6.3 | 24.8 | |
Stromal reaction | |||||||
No | 33 | 28 | 5 (15.2) | 13.3 | 6.3 | 20.2 | -- |
Number of chemotherapy lines | |||||||
Up to 2 | 26 | 22 | 4 (15.4) | 10.2 | 6.2 | 14.2 | 0.013 |
More than 2 | 7 | 6 | 1 (14.3) | 23.5 | 10.8 | 36.2 | |
Age | |||||||
<65 | 12 | 8 | 4 (33.3) | 20.4 | 0.0 | 44.5 | 0.152 |
≥65 | 21 | 20 | 1 (4.8) | 11.0 | 6.4 | 15.5 | |
Number of metastases | |||||||
Up to 2 | 28 | 23 | 5 (17.9) | 11.0 | 6.2 | 15.8 | 0.961 |
More than 2 | 5 | 5 | 0 | 17.9 | 1.3 | 34.5 |
95%CI: confidence interval 95%CI; ULN: upper limit of the normal range.