Table 1. Baseline characteristics of study participants.
| Characteristic | <65 years 317 (37.4%) n (%) | ≥65 years 531 (62.6%) n (%) | p value |
|---|---|---|---|
| Male sex | 178 (56.2) | 310 (58.4) | 0.566 |
| Underlying disease | |||
| Systemic hypertension | 89 (28.1) | 280 (52.9) | <0.001 |
| Diabetes mellitus | 69 (21.8) | 173 (32.7) | 0.001 |
| Neoplasms | 73 (23.0) | 146 (27.6) | 0.142 |
| Congestive heart failure | 12 (3.8) | 73 (13.8) | <0.001 |
| Coronary insufficiency | 18 (5.7) | 72 (13.6) | <0.001 |
| COPD | 7 (2.2) | 67 (12.7) | <0.001 |
| Chronic renal failure | 10 (3.2) | 44 (8.3) | 0.003 |
| Chronic renal failure RRT | 12 (3.8) | 30 (5.7) | 0.255 |
| Liver cirrhosis | 60 (18.9) | 20 (3.8) | <0.001 |
| Solid organ transplantation | 66 (20.8) | 14 (2.6) | <0.001 |
| HIV | 3 (0.9) | 1 (0.2) | 0.151 |
| Number of comorbid conditions | <0.001 | ||
| 0 | 85 (26.8) | 75 (14.1) | |
| 1 | 109 (34.4) | 161 (30.3) | |
| 2 | 80 (25.2) | 168 (31.7) | |
| ≥3 | 43 (13.6) | 127 (23.9) | |
| Source of infection | |||
| Respiratory tract | 144 (45.4) | 307 (57.8) | <0.001 |
| Urinary tract | 51 (16.1) | 85 (16.0) | 1.000 |
| Abdominal | 84 (26.5) | 77 (14.5) | <0.001 |
| Skin and soft tissue | 9 (2.8) | 25 (4.7) | 0.208 |
| Others | 12 (3.8) | 20 (3.8) | 1.000 |
| Bloodstream | 13 (4.1) | 10 (1.9) | 0.078 |
| Unknown | 4 (1.3) | 7 (1.3) | 1.000 |
| Site of diagnosis, n (%) | |||
| Emergency department | 155 (48.9) | 270 (50.8) | 0.619 |
| Hospital floor | 107 (33.8) | 104 (19.6) | <0.001 |
| Intermediary care | 18 (5.7) | 93 (17.5) | <0.001 |
| Intensive care unit | 33 (10.4) | 61 (11.5) | 0.653 |
| Other | 4 (1.3) | 3 (0.6) | 0.434 |
p values are given by χ2 test or Fisher’s exact test for binary variables and Unpaired test for continuous variables. COPD: chronic obstructive pulmonary disease; HIV: human immunodeficiency virus; RRT: renal replacement therapy.