Table 2. Clinical presentation of study patients.
Characteristic | <65 years 317 (37.4%) | ≥65 years 531 (62.6%) | p value |
---|---|---|---|
APACHE II score, median [IQR] | 19 [15-24] | 22 [18-28] | <0.001 |
Arterial lactate (mmol/L), median [IQR] | 2.4 [1.3-4.1] | 2.2 [1.4-3.6] | 0.285 |
Severe sepsis, n (%) | 141 (44.5) | 230 (43.3) | 0.775 |
Septic shock, n (%) | 176 (55.5) | 301 (56.7) | |
Clinical presentation, n (%) | |||
Hypotension | 229 (72.2) | 384 (72.3) | 1.000 |
Lactate ≥4.0mmol/L | 86 (27.7) | 101 (19.7) | 0.008 |
Number of organ dysfunctions, median [IQR] | 2 [2-4] | 3 [2-3] | 0.829 |
Organ dysfunction, n (%) | |||
Circulatory | 230 (72.6) | 361 (68.0) | 0.165 |
Respiratory | 181 (57.1) | 325 (61.2) | 0.248 |
Renal | 136 (42.9) | 205 (38.6) | 0.220 |
CNS | 92 (29.0) | 181 (34.1) | 0.130 |
Hepatic | 19 (6.0) | 17 (3.2) | 0.055 |
Metabolic | 106 (33.4) | 177 (33.3) | 1.000 |
Hematologic | 93 (29.3) | 130 (24.5) | 0.126 |
p values are given by χ2 test for binary variables and Mann-Whitney U test for continuous variables; APACHE II: Acute Physiology and Chronic Health Evaluation II (the score can range from zero to 71, with higher scores indicating more severe illness); IQR: interquartile range; CNS: central nervous system.