Table 4. Univariate and multivariate logistic regression analysis addressing the main risk factors for in-hospital mortality including 848 severe sepsis and septic shock patients.
| Characteristics | Univariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|
| OR | 95%CI | p value | OR | 95%CI | p value | |
| Male sex | 0.82 | 0.61-1.10 | 0.182 | 0.68 | 0.48-0.97 | 0.032 |
| Site of diagnosis | ||||||
| Emergency department | 1.00 | |||||
| Hospital floor | 3.10 | 2.14-4.48 | <0.001 | 2.74 | 1.78-4.22 | <0.001 |
| Intermediary care | 4.93 | 3.15-7.71 | <0.001 | 4.39 | 2.63-7.35 | <0.001 |
| Intensive care unit | 5.78 | 3.59-9.31 | <0.001 | 3.64 | 2.04-6.50 | <0.001 |
| Liver cirrhosis | 2.62 | 1.65-4.18 | <0.001 | 2.13 | 1.22-3.72 | 0.008 |
| Urinary tract infection | 0.30 | 0.18-0.49 | <0.001 | 0.40 | 0.21-0.75 | 0.040 |
| APACHE II score | 1.11 | 1.08-1.13 | <0.001 | 1.08 | 1.05-1.11 | <0.001 |
| Arterial lactate | 1.18 | 1.12-1.25 | <0.001 | 1.14 | 1.06-1.22 | <0.001 |
| Number of organ dysfunction | 1.56 | 1.38-1.76 | <0.001 | 1.21 | 1.04-1.40 | 0.012 |
| Mechanical ventilation | 4.94 | 3.62-6.73 | <0.001 | 1.89 | 1.29-2.78 | 0.001 |
APACHE II: Acute Physiology and Chronic Health Evaluation II (the score can range from zero to 71, with higher scores indicating more severe illness). OR: odds ratio; 95%CI: 95% confidence interval.