Table 3. Characteristics of the patients who died and those who survived.
Characteristic | Survived (n=15) | Died (n=20) | p-value |
---|---|---|---|
Age, yr | 39 (16–60) | 51.5 (20–83) | 0.059 |
Sex | |||
Male | 10 (66.7) | 17 (85.0) | 0.246 |
Female | 5 (33.3) | 3 (15.0) | |
History of smoking | 12 (80.0) | 17 (85.0) | 1.000 |
History of previous TB | 2 (13.3) | 9 (45.0) | 0.069 |
Presence of DM | 2 (13.3) | 6 (30.0) | 0.419 |
Duration of symptoms, day | 40 (2–180) | 40 (7–365) | 0.780 |
Drug resistance | 1 (6.7) | 9 (45.0) | 0.022 |
Scores | |||
APACHE II | 14 (7–21) | 22 (16–32) | <0.001 |
SOFA | 2.5 (1–7) | 9 (2–14) | <0.001 |
Need for IMV | 6 (40.0) | 18 (90.0) | 0.003 |
Need for NIMV | 13 (86.7) | 10 (50.0) | 0.034 |
PaO2/FiO2 | 202 (84–376) | 144 (59–298) | 0.017 |
Blood pH | 7.43 (7.08–7.52) | 7.21 (7.08–7.48) | 0.019 |
WBC, ×103/µL | 7.2 (4.7–42.9) | 12.4 (2–28.6) | 0.386 |
Hematocrit, % | 30.4 (21.5–45) | 29.2 (22–39) | 0.172 |
Albumin, g/dL | 3.1 (1.7–3.8) | 2.4 (1–3.1) | 0.002 |
ALT, U/L | 35 (8–107) | 19.5 (7–146) | 0.766 |
AST, U/L | 59 (11–158) | 41.5 (10–380) | 0.726 |
Sodium, mmol/L | 133 (122–140) | 133.5 (120–151) | 0.569 |
Potassium, mmol/L | 4.4 (3.5–5.1) | 4.3 (2.7–5.9) | 0.358 |
Creatinine, mg/dL | 0.7 (0.2–1.3) | 0.6 (0.2–3.1) | 0.856 |
C-reactive protein, mg/L | 50 (1.5–273) | 22.6 (4.2–187) | 0.806 |
Additional bacterial growth | 11 (73.3) | 15 (75.0) | 1.000 |
Presence of shock | 2 (18.2) | 17 (89.5) | <0.001 |
Multiple organ failure | 2 (13.3) | 14 (70.0) | 0.001 |
Acute renal insufficiency | 3 (20.0) | 10 (50.0) | 0.069 |
Values are presented as median (range) or number (%).
TB: tuberculosis; DM: diabetes mellitus; APACHE: Acute Physiology and Chronic Health Evaluation; SOFA: Sequential Organ Failure Assessment; IMV: invasive mechanical ventilation; NIMV: non-invasive mechanical ventilation; PaO2/FIO2: partial pressure of oxygen/fraction of inspired oxygen; WBC: white blood cell; ALT: alanine aminotransferase; AST: aspartate aminotransferase.