Table 5.
Correlations of vortex formation time and wall shear stress with pulmonary artery dimensions, flow parameters and right ventricular function in patients with PAH
Variables | Correlation with vortex formation time (%cardiac cycle) | Correlation with maximum WSS at MPA (Pa) | Correlation with mean WSS at MPA (Pa) | ||||
---|---|---|---|---|---|---|---|
r | p value | r | p value | r | p value | ||
Geometry of MPA | Diameter (mm) | −0.257 | 0.504 | 0.035 | 0.928 | −0.019 | 0.962 |
Area (mm2) | −0.212 | 0.643 | 0.035 | 0.928 | 0.001 | 0.999 | |
Blood flow parameter at MPA | Maximum blood flow velocity (m/sec) | −0.391 | 0.299 | 0.348 | 0.359 | 0.068 | 0.862 |
Mean blood flow velocity (m/sec) | 0.374 | 0.321 | −0.091 | 0.817 | −0.021 | 0.957 | |
Maximum blood flow volume (L/min) | −0.621 | 0.080 | 0.238 | 0.537 | −0.115 | 0.768 | |
Mean blood flow volume (L/min) | −0.004 | 0.992 | −0.119 | 0.760 | −0.232 | 0.546 | |
SV (mL) | −0.025 | 0.948 | −0.122 | 0.755 | −0.262 | 0.496 | |
WSS at MPA | Maximum WSS (pa) | −0.354 | 0.350 | – | – | 0.741 | 0.022 |
Mean WSS (Pa) | −0.339 | 0.337 | 0.741 | 0.022 | – | – | |
RV functional parameter | RVEF (%) | −0.892 | 0.003 | 0.546 | 0.162 | 0.592 | 0.112 |
RVEDV (mL) | 0.408 | 0.316 | 0.112 | 0.791 | −0.417 | 0.305 | |
RVEDVI (mL/m2) | 0.366 | 0.373 | 0.116 | 0.784 | −0.427 | 0.291 | |
RVESV (mL) | 0.738 | 0.037 | −0.204 | 0.628 | −0.525 | 0.182 | |
RVESVI (mL/m2) | 0.736 | 0.038 | −0.221 | 0.599 | −0.546 | 0.162 |
RV right ventricle, MPA main pulmonary artery, SV stroke volume, WSS wall shear stress, RVEF right ventricular ejection fraction, RVEDV right ventricular end diastolic volume, RVEDVI right ventricular end diastolic volume index, RVESV right ventricular end systolic volume, RVESVI right ventricular end systolic volume index