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. 2016 Mar 11;468:1171–1181. doi: 10.1007/s00424-016-1806-9

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Effects of CFTRinh-172 on the adenosine stimulation in Capan-1 monolayers. a The representative trace demonstrates the increase observed in negative V _te in response to adenosine (Ado; 100 μM) (phase II) and the inhibition by CFTRinh-172 (20 μM) (phase IV) on the luminal membrane. b Summary of V _te recordings (n = 5). Numbers (I, II, III, and IV) correspond to the control and test periods of the experiment depicted in a. *P < 0.05. c An equivalent short-circuit current (I _sc) trace from the same experiment as shown in a. d Summary of the effects of adenosine and CFTRinh-172 on I _sc (n = 5)