Table 3.

Analyses of association between CR2 gene polymorphisms and the risk of ONFH in SLE patients.

SNP rs number	Genotype	Frequencies (%)		Allele		Dominant		Recessive
		Controls (SLE)	Cases (SLE_ONFH)	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
rs3813946	TT	102 (71.83)	35 (71.43)
	CT	39 (27.46)	10 (20.41)	1.33 (0.73–2.45)	0.353	1.02 (0.50–2.10)	0.957	12.5 (1.37–115)	0.016∗
	CC	1 (0.7)	4 (8.16)
rs311306	GG	108 (72.97)	35 (70.0)
	CG	39 (26.35)	10 (20.0)	1.56 (0.86–2.81)	0.141	1.16 (0.57–2.34)	0.685	16.3 (1.86–143)	0.004∗
	CC	1 (0.68)	5 (10.0)
rs1567190	TT	49 (33.11)	22 (44.0)
	CT	74 (50.0)	22 (44.0)	0.72 (0.45–1.15)	0.164	0.63 (0.33–1.21)	0.165	0.67 (0.26–1.74)	0.411
	CC	25 (16.89)	6 (12.0)
rs17615 (S639N)	GG	108 (73.47)	36 (73.47)
	AG	39 (26.53)	10 (20.41)	1.28 (0.68–2.40)	0.450	1.0 (0.48–2.08)	1		0.015∗
	AA	0 (0)	3 (6.12)
rs17045328	AA	78 (53.06)	31 (64.58)
	AG	61 (41.5)	14 (29.17)	0.74 (0.43–1.29)	0.292	0.62 (0.32–1.22)	0.163	1.16 (0.30–4.55)	0.734∗
	GG	8 (5.44)	3 (6.25)
rs12032512	CC	47 (31.76)	16 (32.0)
	CG	78 (52.7)	23 (46.0)	1.14 (0.72–1.79)	0.587	0.99 (0.50–1.97)	0.975	1.53 (0.69–3.42)	0.295
	GG	23 (15.54)	11 (22.0)
rs6690215	CC	41 (27.7)	20 (40.0)
	CT	77 (52.03)	17 (34.0)	0.88 (0.55–1.38)	0.569	0.58 (0.29–1.12)	0.103	1.38 (0.65–2.92)	0.396
	TT	30 (20.27)	13 (26.0)
rs17045468	CC	79 (53.74)	30 (60.0)
	CT	61 (41.5)	17 (34.0)	0.87 (0.51–1.49)	0.616	0.78 (0.40–1.49)	0.442	1.28 (0.32–5.14)	0.716∗
	TT	7 (4.76)	3 (6.0)

Genotype distributions are shown as number (%). Chi-square P values and odds ratio (95% CI) are shown. OR: odds ratio; CI: confidence interval.

^∗Fisher's exact test.