Table 2.
Correlation between the protein expression of Notch3 and pS6 proteins and clinicopathological parameters in patients with ovarian epithelial cancer.
| Characteristics | Cases, n | Notch3 expression, n | p value | pS6 expression, n | p value | ||||
|---|---|---|---|---|---|---|---|---|---|
| − | + | ++ | − | + | ++ | ||||
| Age, yrs | |||||||||
| <50 | 79 | 7 | 19 | 53 | 0.947 | 6 | 37 | 36 | 0.558 |
| ≥50 | 41 | 3 | 11 | 27 | 6 | 12 | 23 | ||
|
| |||||||||
| Clinical stages | |||||||||
| I~II | 41 | 8 | 17 | 16 | 0.000 | 7 | 22 | 12 | 0.001 |
| III~IV | 79 | 2 | 13 | 64 | 5 | 27 | 47 | ||
|
| |||||||||
| Pathological grading | |||||||||
| G1 | 17 | 7 | 7 | 3 | 0.000 | 5 | 7 | 5 | 0.001 |
| G2 | 40 | 3 | 17 | 20 | 6 | 22 | 12 | ||
| G3 | 63 | 0 | 6 | 57 | 1 | 20 | 42 | ||
|
| |||||||||
| Histologic type | |||||||||
| Serous cystadenocarcinoma | 77 | 1 | 19 | 57 | 0.006 | 3 | 31 | 43 | 0.011 |
| Mucinous cystadenocarcinoma | 43 | 9 | 11 | 23 | 9 | 18 | 16 | ||
|
| |||||||||
| Lymph node metastasis | |||||||||
| Yes | 37 | 0 | 5 | 32 | 0.001 | 0 | 5 | 32 | 0.000 |
| No | 83 | 10 | 25 | 48 | 12 | 44 | 27 | ||
|
| |||||||||
| Ascites | |||||||||
| Yes | 70 | 2 | 9 | 59 | 0.000 | 2 | 21 | 47 | 0.000 |
| No | 50 | 8 | 21 | 21 | 10 | 28 | 12 | ||