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. 2016 Jul 13;16:467. doi: 10.1186/s12885-016-2491-y

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Kaplan-Meier curves for progression-free survival (PFS; median 3.0 months versus 2.4 months; Log-rank P-value = 0.01) as well as overall survival (OS; median 14.0 months versus 5.6 months; Log-rank P-value < 0.0001) for patients who achieved chemotherapy induced neutropenia (CIN) ≥ grade 2 CTCAE (red line – 69 patients (46.3 %) – CIN-1-month positive) as compared to those who did NOT have ≥ grade 2 CIN at the 1-month mark (blue line – 80 patients (53.7 %) – CIN-1-month negative) after starting treatment with TAS-102