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. 2016 Jul 13;16:328. doi: 10.1186/s12879-016-1682-0

Table 3.

Medications taken by 460 Finnish travelers during the trip. The medications are categorized according to indication. The data are presented as numbers and percentages of travelers

Number (%a)
Prophylactic antimalarial use among those recommended (missing data = 6) 289 (98)
 Atovaquone and proguanil 135 (30)
 Mefloquine 70 (15)
 Doxycycline 55 (12)
 Chloroquine 25 (6)
 Other / not known 2 (0)
 Changed drug b 2 (0)
 Failure in use c 7 (2)
Antimicrobials (other than doxicycline) (missing data = 0) d 81 (18)
 Fluoroquinolone 53 (12)
 Macrolide 9 (2)
 Nitroimidazole (metronidazole or tinidatzole) 7 (2)
 Amoxicillin 5 (1)
 Tetracycline 1 (0)
 Other / not known 25 (5)
 Two or more antimicrobials (without doxycycline) 15 (3)
Treatment for malaria (missing data = 0) e 4 (1)
Gastrointestinal medication (missing data = 0) 127 (28)
 Loperamide 115 (25)
 Medicinal charcoal 7 (2)
 Other (laxative, spasmolyte, co-phenotrope) 10 (2)
 Two or more gastrointestinal medications 5 (1)
Analgesic (missing data = 0) 123 (27)
 NSAID 67 (15)
 Paracetamol 59 (13)
 Other / not known 16 (3)
 Two or more analgesics 18 (4)
Antiemetic (missing data = 0) 4 (1)
PPI or antacid (missing data = 4) 36 (8)
 PPI 26 (6)
 Antacid (salts/H2) 10 (2)
Probiotics and prebiotics (missing data = 3) f 270 (59)
 Starting before travel 11 (2)
 Using only during travel 123 (27)
 Starting before and using during travel 136 (30)

a Total use of all travelers among those from whom information was available

b Each of these changed the medication from doxycycline to mefloquine

c Did not use as recommended (2 did not take at all, 1 stopped because of adverse effects, 4 used irregularly): atovaquone/proguanil (4), doxycycline (2), mefloquine (1); 10 had prescription but did not enter malaria area; 33 traveled to endemic countries yet visited only low prevalence areas

d 52 (11 % of all) used antimicrobials for TD

e All in Africa, three of four were tested; two negative, one positive

f If only product mentioned, presumed to be used while traveling