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Five- to 7-week-old female p53+/+ (n = 14) and p53−/− (n = 14) ICR mice were inoculated with 100 PFU of HSV-1(F) intracranially. At 6 days postinfection, lymphocytes in the brain were harvested and CD11b+ Ly6G+ cells were quantified by flow cytometry. Each data point is the total number of CD11b+ Ly6G+ cells in the brain of one mouse. The horizontal bars indicate the mean for each group. Statistical significance was determined by the two-tailed Student t test.
