TABLE 1.
Virus | ORF | Mean πN ± SE | Mean πS ± SE | P valueb |
---|---|---|---|---|
SIVver | gag*** | 0.002387 ± 0.00029 | 0.02153 ± 0.00185 | 1.24 × 10−35 |
pol*** | 0.001595 ± 0.00014 | 0.01808 ± 0.00101 | 8.59 × 10−70 | |
vif*** | 0.002705 ± 0.00038 | 0.00939 ± 0.00216 | 5.05 × 10−6 | |
vpx*** | 0.001078 ± 0.00033 | 0.01158 ± 0.00319 | 1.62 × 10−6 | |
tat | 0.006165 ± 0.00118 | 0.00351 ± 0.00137 | 0.189 | |
rev*** | 0.005369 ± 0.00117 | 0.02000 ± 0.00324 | 9.87 × 10−6 | |
env*** | 0.006657 ± 0.00057 | 0.02102 ± 0.00138 | 1.20 × 10−30 | |
nef*** | 0.004809 ± 0.00069 | 0.01738 ± 0.00218 | 1.19 × 10−10 | |
SPgVver | SPgV*** | 0.000214 ± 0.00003 | 0.00208 ± 0.00019 | 7.00 × 10−33 |
DMVV-1 | 1a*** | 0.000954 ± 0.00008 | 0.01208 ± 0.00078 | 9.02 × 10−65 |
TF | 0.001643 ± 0.00035 | 0.00287 ± 0.00088 | 0.0251 | |
1b*** | 0.000385 ± 0.00006 | 0.01289 ± 0.00071 | 1.70 × 10−82 | |
2a′*** | 0.001221 ± 0.00027 | 0.01175 ± 0.00158 | 5.73 × 10−13 | |
3′*** | 0.002715 ± 0.00052 | 0.01108 ± 0.00203 | 1.96 × 10−6 | |
4′*** | 0.001358 ± 0.00036 | 0.01023 ± 0.00195 | 1.96 × 10−8 | |
2a*** | 0.001255 ± 0.00044 | 0.01212 ± 0.00262 | 5.41 × 10−5 | |
2b** | 0.001889 ± 0.00032 | 0.00551 ± 0.00109 | 0.000391 | |
3*** | 0.003706 ± 0.00064 | 0.01117 ± 0.00179 | 3.34 × 10−5 | |
4 | 0.005481 ± 0.00082 | 0.00730 ± 0.00124 | 0.0433 | |
5a* | 0.007072 ± 0.00153 | 0.02214 ± 0.00511 | 0.000655 | |
5 | 0.009080 ± 0.00181 | 0.01100 ± 0.00195 | 0.156 | |
6*** | 0.000371 ± 0.00014 | 0.00705 ± 0.00180 | 4.45 × 10−6 | |
7*** | 0.001382 ± 0.00033 | 0.00887 ± 0.00197 | 2.68 × 10−5 |
Bonferroni significance levels were used to account for the use of 23 tests, one for each open reading frame, as follows: *, α value of <0.05 if the P value was <0.00217; **, α value of <0.01 if the P value was <0.000435; ***, α value of <0.001 if the P value was <4.35 × 10−5. Significance levels refer to a paired t test where πN equals πS.
Determined by a paired t test.