Table 4.
Clinical complications and outcome by age category and stratified by treatment strategy (n = 3475)
| Age category | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variable | 25–64 years | 65–74 years | 75–84 years | p Value | ||||||
| Treatment strategy | All n = 1329 (100) | IT n = 1187 (89.3) | CT n = 142 (10.7) | All n = 1083 (100) | IT n = 891 (82.3) | CT n = 192 (17.7) | All n = 1063 (100) | IT n = 683 (64.2) | CT n = 380 (35.8) | <0.0001 |
| Complications during hospital stay | ||||||||||
| Cardiac arrest | 76 (5.7) | 58 (4.9) | 18 (12.7) | 110 (10.2) | 79 (8.9) | 31 (16.2) | 176 (16.6) | 102 (14.9) | 74 (19.5) | <0.0001 |
| Cardiogenic shock | 54 (4.1) | 48 (4.0) | 6 (4.2) | 77 (7.1) | 66 (7.4) | 11 (5.7) | 101 (9.5) | 75 (11.0) | 26 (6.8) | <0.0001 |
| Ventricular fibrillation | 32 (2.4) | 29 (2.4) | 3 (2.1) | 32 (3.0) | 27 (3.0) | 5 (2.6) | 31 (2.9) | 25 (3.7) | 6 (1.6) | 0.65 |
| Ventricular tachycardia | 109 (8.2) | 105 (8.9) | 4 (2.8) | 66 (6.1) | 60 (6.7) | 6 (3.1) | 54 (5.1) | 41 (6.0) | 13 (3.4) | 0.007 |
| Bradycardia | 76 (5.7) | 72 (6.1) | 4 (2.8) | 71 (6.6) | 67 (7.5) | 4 (2.1) | 63 (5.9) | 51 (7.5) | 12 (3.2) | 0.68 |
| Re-infarction | 10 (0.8) | 10 (0.8) | 0 | 18 (1.7) | 13 (1.5) | 5 (2.6) | 26 (2.5) | 20 (2.9) | 6 (1.6) | 0.04 |
| Stroke | 5 (0.4) | 5 (0.4) | 0 | 9 (0.8) | 7 (0.8) | 2 (1.0) | 8 (0.8) | 5 (0.7) | 3 (0.8) | 0.32 |
| Pulmonary edema | 30 (2.3) | 25 (2.1) | 5 (3.5) | 43 (4.0) | 33 (3.7) | 10 (5.2) | 57 (5.4) | 41 (6.0) | 16 (4.2) | 0.0003 |
| Any major bleeding complicationa | 13 (1.0) | 11 (0.9) | 2 (1.4) | 19 (1.8) | 14 (1.6) | 5 (2.6) | 22 (2.1) | 16 (2.3) | 6 (1.6) | 0.08 |
| Any in-hospital complication (without cardiac arrest) | 254 (19.1) | 236 (19.9) | 18 (12.7) | 243 (22.4) | 208 (23.3) | 35 (18.2) | 249 (23.4) | 185 (27.1) | 64 (16.8) | 0.02 |
| Outcome | ||||||||||
| 28-day-case fatality | 44 (3.3) | 28 (2.4) | 16 (11.3) | 74 (6.8) | 44 (4.9) | 30 (15.6) | 138 (13.0) | 64 (9.4) | 74 (19.5) | <0.0001 |
| Death during hospital stay | 43 (3.2) | 28 (2.4) | 15 (10.6) | 74 (6.9) | 45 (5.1) | 30 (15.6) | 146 (13.7) | 72 (10.5) | 74 (19.5) | <0.0001 |
Data are presented as number (percentage). P values were calculated for comparison of the age categories
IT invasive therapy, CT conservative therapy
a Major bleeding complication: intracranial or retroperitoneal or any other major spontaneous bleeding