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. 2016 Jul 13;16:461. doi: 10.1186/s12885-016-2530-8

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Relative tumor volumes in mice CT26 colon cancer cell line-induced tumor treated with LacZ, zeo, VP3, shCD147/2 and VP3-shCD147/2 combination. On long-term, combination VP3-shCD147/2 treatments were effective in inhibiting tumor growth than either VP3 or shCD147/2 alone. The plasmids used in the treatments were pVIVO1-GFP/LacZ (LacZ), psiRNA-h7SKzeo (zeo), pVIVO1-GFP/VP3 (VP3) and psiRNA-CD147/2 (shCD147/2)