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. 2016 Jul 13;11:52. doi: 10.1186/s13024-016-0118-z

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Phosphorylated PRAS40 levels are increased in AD patients. a Western blots of proteins extracted from the inferior temporal gyrus of human control (CTL; n = 10) and AD brains (n = 9). Blots were probed with the indicated antibodies. The descriptive information for each patient (numbered above the blots) are reported in Table 1. b Quantitative analysis of the blot shows that phosphorylated PRAS40 levels were significantly higher in AD compared to CTL cases (p = 0.0325). Quantitative analyses of the blots were obtained by normalizing PRAS40 levels to β-Actin, used as a loading control. Error bars represent mean ± SEM