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Diagnostic and prognostic criteria for inclusion
| Biomarker function | Description | Biomarkers identified (n) | Number of studies in which biomarkers were identified (n) |
|---|---|---|---|
| Diagnostic | D1: SJIA versus other non-arthritis conditions or HC | 36 | 48 |
| D2: SJIA versus other JIA subtypes | 25 | 25 | |
| Prognostic | P1: for flare (or relapse) | 14 | 16 |
| P2: for increased disease activity and/or the discrimination of active and inactive disease | 15 | 21 | |
| P3: for MAS or discriminating MAS from SJIA flare | 7 | 12 |
