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. 2016 Jul 13;16:462. doi: 10.1186/s12885-016-2536-2

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — B16F10 and LLC tumours that had previously received cell-based Reovirus vaccine as therapy for established tumour were excised and analysed for cytokine production. Both groups were evaluated – those that had received the vaccine s.c. and IV. a B16F10 tumours showed no particular pattern of cytokine production post exposure relative to route of vaccine administration. b LLC tumours showed a down-regulation of cytokine levels in almost all evaluated. Statistical significance is indicated by the stars above each bar (*P < 0.05, **P < 0.01, ***P < 0.0001)