Figure 4. mThy1-hAβPP751 Tg mice display preserved motor function in the Open Field.
A) Total activity in the Open Field of the non-Tg and mThy1-hAβPP751 Tg mice at 3, 6, and 9 months of age. B) Gender-stratification of the total activity in the mThy1-hAβPP751 Tg mice at 3, 6, and 9 months of age. C) Thigmotactic behavior in the non-Tg and mThy1-hAβPP751 Tg mice at 3, 6, and 9 months of age. D) Gender-stratification of thigmotaxis in the mThy1-hAβPP751 Tg mice at 3, 6, and 9 months of age. Data are presented as means ± SEM. * Indicates a significant difference between 3 and 6 month old non-Tg or 3 and 6 month old mThy1-hAβPP751 Tg mice with p<0.05 by one-way ANOVA. ** Indicates a significant difference between non-Tg and mThy1-hAβPP751 Tg mice with p<0.01 by one-way ANOVA.