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. Author manuscript; available in PMC: 2016 Jul 14.
Published in final edited form as: J Alzheimers Dis. 2011;25(2):231–243. doi: 10.3233/JAD-2011-101866

Figure 6. mThy1-hAβPP751 Tg mice display age-related, longitudinal accumulation of Aβ in the cortex and hippocampus.

Figure 6

Aβ plaques were visualized using the 6E10 antibody to AA1-17 of the hAβ protein.

A) Plaque size at 3, 6, and 9 months of age in the cortex of mThy1-hAβPP751 Tg mice. B) Plaque number at 3, 6, and 9 months of age in the cortex of mThy1-hAβPP751 Tg mice. C) Plaque size at 3, 6, and 9 months of age in the hippocampus of mThy1-hAβPP751 Tg mice. D) Plaque number at 3, 6, and 9 months of age in the hippocampus of mThy1-hAβPP751 Tg mice. Insets in the bars at 9 months indicate gender-related differences in cortical and hippocampal plaque size and number. Data are presented as means ± SEM.* Indicates a significant difference with p<0.05 by one-way ANOVA. ** Indicates a significant difference with p<0.01 by one-way ANOVA. *** Indicates a significant difference with p<0.001 by one-way ANOVA