Skip to main content
. 2016 Jun;13(2):206–214. doi: 10.20892/j.issn.2095-3941.2015.0070

Table1.

The influence of VEGF on different immune and cancer cells

Cell type The influence of VEGF on the cell Reference
VEGF, vascular endothelial growth factor; DC, dendritic cell; mDC, myeloid DC; pDC, plasmacytoid DC; OAD, obliterative airway disease.
Dendritic cell Inhibit the differentiation of DC in the hematopoietic process 30
Influence the function and maturation of DC 29
Increase the mDC and pDC in lung 32
Enable DC to differentiate into endothelial-like cell 33
Enable DC to get an angiogenic property 34
Macrophage Prevent inflammation during bacterial infection 35
Mediate the infiltration of macrophage in the lung 36
T lymphocyte Cause thymic atrophy 37
Costimulate IFN-γ production, increase chemotaxis 38
Induce epithelial activation, neutrophil chemotaxis in OAD 39
Treg Promote the induction and maintenance of Treg in the tumor site 40
Chemotaxis for Treg 5
Tumor cell Increase the migration, cell mobility and invasiveness of tumor cells 41- 43
Promote cancer stemness 44