Table 1.
Characteristics of the study population
| Characteristic | NRT |
SCRT-I |
SCRT-D |
LCCRT |
Other |
PORT |
Any radiotherapy | Total | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | n | % | n | % | n | % | |||||
| Age group | ≤60 | 929 | 39.6 | 282 | 12.0 | 15 | 0.6 | 951 | 40.5 | 109 | 4.6 | 63 | 2.7 | 1420 | 60.5 | 2348 |
| 61–70 | 1484 | 48.6 | 377 | 12.3 | 27 | 0.9 | 933 | 30.5 | 166 | 5.4 | 71 | 2.3 | 1574 | 51.5 | 3056 | |
| 71–80 | 1509 | 53.3 | 362 | 12.8 | 40 | 1.4 | 731 | 25.8 | 129 | 4.6 | 61 | 2.2 | 1323 | 46.7 | 2832 | |
| >80 | 694 | 71.9 | 94 | 9.7 | 28 | 2.9 | 98 | 10.2 | 31 | 3.2 | 20 | 2.1 | 271 | 28.1 | 965 | |
| Gender | Male | 2889 | 48.2 | 773 | 12.9 | 69 | 1.2 | 1849 | 30.8 | 276 | 4.6 | 138 | 2.3 | 3105 | 51.8 | 5994 |
| Female | 1727 | 53.9 | 340 | 10.6 | 41 | 1.3 | 864 | 26.9 | 159 | 5.0 | 76 | 2.4 | 1480 | 46.1 | 3207 | |
| Dukes stage at diagnosis | A | 1289 | 64.7 | 253 | 12.7 | 13 | 0.7 | 345 | 17.3 | 76 | 3.8 | 17 | 0.9 | 704 | 35.3 | 1993 |
| B | 1239 | 54.7 | 282 | 12.5 | 31 | 1.4 | 559 | 24.7 | 107 | 4.7 | 46 | 2.0 | 1025 | 45.3 | 2264 | |
| C | 1441 | 45.5 | 375 | 11.8 | 32 | 1.0 | 1057 | 33.4 | 164 | 5.2 | 97 | 3.1 | 1725 | 54.5 | 3166 | |
| D | 299 | 50.1 | 39 | 6.5 | 9 | 1.5 | 191 | 32.0 | 34 | 5.7 | 25 | 4.2 | 298 | 49.9 | 597 | |
| Unknown | 348 | 29.5 | 164 | 13.9 | 25 | 2.1 | 561 | 47.5 | 54 | 4.6 | 29 | 2.5 | 833 | 70.5 | 1181 | |
| Charlson comorbidity score | 0 | 3645 | 48.1 | 957 | 12.6 | 91 | 1.2 | 2349 | 31.0 | 355 | 4.7 | 176 | 2.3 | 3928 | 51.9 | 7573 |
| 1 | 655 | 57.8 | 111 | 9.8 | 12 | 1.1 | 268 | 23.7 | 63 | 5.6 | 24 | 2.1 | 478 | 42.2 | 1133 | |
| 2 | 204 | 60.4 | 32 | 9.5 | 5 | 1.5 | 72 | 21.3 | 14 | 4.1 | 11 | 3.3 | 134 | 39.6 | 338 | |
| ≥3 | 112 | 71.3 | 13 | 8.3 | 2 | 1.3 | 24 | 15.3 | 3 | 1.9 | 3 | 1.9 | 45 | 28.7 | 157 | |
| IMD income category | Most affluent | 1072 | 53.2 | 226 | 11.2 | 19 | 0.9 | 542 | 26.9 | 109 | 5.4 | 46 | 2.3 | 942 | 46.8 | 2014 |
| 2 | 1115 | 51.9 | 279 | 13.0 | 20 | 0.9 | 622 | 29.0 | 74 | 3.4 | 37 | 1.7 | 1032 | 48.1 | 2147 | |
| 3 | 995 | 50.4 | 241 | 12.2 | 21 | 1.1 | 577 | 29.2 | 92 | 4.7 | 49 | 2.5 | 980 | 49.6 | 1975 | |
| 4 | 816 | 48.2 | 212 | 12.5 | 28 | 1.7 | 521 | 30.8 | 70 | 4.1 | 46 | 2.7 | 877 | 51.8 | 1693 | |
| Least affluent | 618 | 45.0 | 155 | 11.3 | 22 | 1.6 | 451 | 32.9 | 90 | 6.6 | 36 | 2.6 | 754 | 55.0 | 1372 | |
| Operation type | APE | 550 | 25.4 | 334 | 15.4 | 45 | 2.1 | 1049 | 48.4 | 160 | 7.4 | 31 | 1.4 | 1619 | 74.6 | 2169 |
| AR | 3191 | 57.9 | 662 | 12.0 | 44 | 0.8 | 1312 | 23.8 | 214 | 3.9 | 90 | 1.6 | 2322 | 42.1 | 5513 | |
| Hartmanns | 407 | 54.1 | 62 | 8.2 | 14 | 1.9 | 195 | 25.9 | 38 | 5.1 | 36 | 4.8 | 345 | 45.9 | 752 | |
| Other | 468 | 61.0 | 55 | 7.2 | 7 | 0.9 | 157 | 20.5 | 23 | 3.0 | 57 | 7.4 | 299 | 39.0 | 767 | |
| Total | 4616 | 50.2 | 1113 | 12.1 | 110 | 1.2 | 2713 | 29.5 | 435 | 4.7 | 214 | 2.3 | 4585 | 49.8 | 9201 | |
NRT, no radiotherapy; SCRT-I, short-course radiotherapy with immediate surgery; SCRT-D, short-course radiotherapy with delayed surgery; LCCRT, long-course chemoradiotherapy; ORT, other radiotherapy; PORT, postoperative radiotherapy; IMD, index of multiple deprivation; APE, abdominoperineal excision; AR, anterior resection.