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. Author manuscript; available in PMC: 2017 Jun 15.
Published in final edited form as: Cancer Res. 2016 May 23;76(12):3484–3495. doi: 10.1158/0008-5472.CAN-15-2663

Figure 3. Cilengitide treatment enhanced tumor growth and increased M2 TAM population.

Figure 3

(A) Experimental schema. 1×105 PyMT-BO1-GFP-Luc cells were injected into MFP of 8-week-old female WT mice (n=5). Starting at day 10 after tumor cell injection, mice were treated daily with cilengitide for 5 days. At day 14, all mice were sacrificed. (B) Tumor growth was measured at the indicated time points by BLI. (C) Tumor weight at day 14. (D) TAM populations in tumor tissue were analyzed by FACS. Data represent mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001.