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. 2016 Jul 12;111(1):178–184. doi: 10.1016/j.bpj.2016.05.035

Figure 3.

Figure 3

(Left) The myosin head, with overlay of crystal structures 1FMV (M∗) and 1VOM (M∗∗), showing a conformational change within the force-generating region. Spheres: engineered labeling sites, showing the predicted shortening of distance between residues 639 and 498 (arrows) during the recovery stroke. (Right) Gaussian distance distributions of the FRET pair within the myosin head (K498C:A639C) without (dashed line) and with (solid line) Ficoll70 in solution. To see this figure in color, go online.