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AQP4 single-channel (unit) water permeabilities (mean ± SE) determined by osmotic-gradient experiments with proteoliposomes (solid circles) and by MD simulations (open triangles) plotted versus bilayer hydrocarbon thickness. The lipid compositions are given in the caption to Fig. 2 for the osmotic-gradient experiments and are C(22:1)(22:1)PC and (C14:0)(C14:0)PC for the simulations.
