Table 4.
Characteristics | Relapse group (N = 2) | Cure group (N = 31) | P value |
---|---|---|---|
Age (years), median (range) | 42 (31–53) | 30 (4–56) | 0.19 |
Male, n (%) | 2 (100) | 20 (67) | 0.48 |
Returning from south Asia, n (%) | 2 (100) | 25 (78) | 0.67 |
Typhoid vaccination within 2 years, n (%) | 0 (0) | 3 (1) | 0.78 |
Time from onset to treatment initiation (days), median (range) | 7 (7–7) | 5 (0–27) | 0.035 |
Fulfilled the sepsis definition, n (%) | 1 (33) | 14 (43) | 0.76 |
Total leucocytes (× 103/μL), median (range) | 4.4 (3.2–5.6) | 5.3 (1.1–11.7) | 0.39 |
CRP (mg/L), median (range) | 65 (32–99) | 49 (11–218) | 0.88 |
Time to positive blood culture (hours), median (range) (N = 25) | 17 (16–18) | 16 (6–45) | 0.96 |
Time to reach defervescence (days), median (range) | 9 (5–13) | 5 (2–12) | 0.24 |
Total treatment period (days), median (range) | 13 (11–15) | 14 (8–21) | 0.66 |
Treatment period after defervescence (days), median (range) | 4 (2–4) | 8 (1–16) | 0.14 |
Symptomatic treatment failure*, n (%) | 1 (50) | 5 (16) | 0.022 |
CRP = C-reactive protein.
Defined as time to reach defervescence > 7 days.