Figure 3.

Maximum likelihood tree of 76 DENV-2 E gene sequences (1,485 bp) including eight Costa Rican strains (black rectangle), three obtained from this study (bold font), and five obtained from GenBank (italic font). Significant bootstrap values (≥ 70) are indicated at the respecting nodes. The sequences were named according to reference number/country/year of collection or isolation. Major clades and subclades comprising Costa Rican strains are indicated with numbers and letters, respectively.