Table 2.

Q fever immunofluorescence serological profiles of acute and chronic Q fever patients

Infection type and patient number	Day of sample*	Antibody to phase 2				Antibody to phase 1
		Coxiella burnetii antigen				C. burnetii antigen
		IgM	IgG	IgA	Total	IgM	IgG	IgA	Total
Acute Q fever
174 (adult)	0	Neg	Neg	Neg	Neg	Neg	Neg	Neg	Neg
	14	≥ 3,200	800	Neg	≥ 3,200	Neg	Neg	Neg	Neg
	44	400	≥ 3,200	400	≥ 3,200	200	200	200	200
176 (adult)	0	Neg	Neg	Neg	Neg	Neg	Neg	Neg	Neg
	1	50	25	Neg	50	Neg	Neg	Neg	Neg
	15	≥ 3,200	≥ 3,200	Neg	≥ 3,200	100	Neg	Neg	100
267 (adult)	0	Neg	Neg	Neg	Neg	Neg	Neg	Neg	Neg
	4	≥ 3,200	100	50	≥ 3,200	Neg	Neg	Neg	Neg
	11	≥ 3,200	≥ 3,200	50	≥ 3,200	200	Neg	Neg	200
Chronic Q fever
271 (child: chronic osteomyelitis)	0	Neg	≥ 3,200	Neg	≥ 3,200	Neg	≥ 3,200	200	≥ 3,200
	198	Neg	≥ 3,200	Neg	≥ 3,200	Neg	≥ 3,200	200	≥ 3,200
	438	Neg	≥ 3,200	50	≥ 3,200	Neg	≥ 3,200	400	≥ 3,200
243 (adult: chronic endocarditis)	0	Neg	≥ 3,200	≥ 3,200	≥ 3,200	50	≥ 3,200	≥ 3,200	≥ 3,200
	446	Neg	≥ 3,200	≥ 3,200	≥ 3,200	Neg	≥ 3,200	≥ 3,200	≥ 3,200
	1,026	Neg	800	100	800	Neg	1,600	800	1,600
199† (adult: acute to chronic endocarditis)	0	≥ 3,200	Neg	Neg	≥ 3,200	Neg	Neg	Neg	Neg
	10	≥ 3,200	≥ 3,200	200	≥ 3,200	Neg	Neg	Neg	Neg
	1,825 (5 years)	Neg	1,600	Neg	1,600	Neg	≥ 3,200	≥ 3,200	≥ 3,200

Neg = negative.

^*The day 0 sample would usually be within 1 week of onset of illness.

^†Patient 199 was first diagnosed as acute Q fever, and 5 years later, represented with chronic Q fever.