Figure 2.

Cage assembly diagrams for clathrin, for 1000 triskelia at a concentration of 10⁻³σ⁻³, combined with model APs clicking to the ends of the TDs and the ankles of clathrin, (a) as a function of the clathrin-clathrin binding strength ε and the clathrin-AP clicking strength ζ, at an AP/clathrin ratio of 3, and (b) as a function of the AP concentration (for AP/clathrin ratios from 0 to 3) and the clathrin-AP clicking strength, at a clathrin-clathrin binding strength of $ϵ=6k_{\text{B}}T$. The markers denote parameter combinations that result in the self-assembly of cages (a green circle if cages are also formed in the absence of APs; a blue circle if assembly only proceeds in the presence of APs), combinations that do not yield cages (red crosses), and conditions where cages do not assemble spontaneously but preassembled cages appear stable (red cross in red circle). The dashed lines indicate the approximate locations of phase boundaries, as discussed in more detail in the main text. To see this figure in color, go online.