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. 2016 Jan 13;149(5):1215–1222. doi: 10.1016/j.chest.2015.11.009

Table 5.

Proportion of UIP Diagnoses on Chest CT Scans Relative to the rs35705950 Single Nucleotide Polymorphism

CT Imaging Scoring System and MUC5B Genotype UIP, No. (%)
Inconsistent With UIP Indeterminate for UIP Probable UIP UIP
Current study
 GG 145 (31) 175 (37) 79 (17) 76 (16)
 GT/TT 183 (20) 324 (36) 191 (21) 204 (23)
Possible UIP
Current guidelines
 GG 145 (31) 254 (54) 76 (16)
 GT/TT 183 (20) 515 (57) 204 (23)

In a small subset of subjects, concordant diagnosis could not be established and were excluded from this portion of the analysis. χ2P < .0001. UIP = usual interstitial pneumonitis. See Table 1 legend for expansion of other abbreviations.