Table 2.
Hematologic neoplasm | Cases n (%) |
D-SPEP n (%) |
F-SPEP n (%) |
Subtypes (n) | Median nadir CD4: cells/ul (IQ range)a |
Median CD4 within 6 months of diagnosis (IQ range)a |
Median HIV VL within 6 months of diagnosis copies/ ml (IQ range)a |
---|---|---|---|---|---|---|---|
Plasma cell neoplasms | 6 (2.6) | 5 (83.3) | 0 | Multiple myeloma (4) Immature plasma cell tumor (2) | 224 (60–486) | 282 (146–720) | 245 (47–2947) |
High grade lymphomas | 199 (86.9) | 0 | 12 (6) | DLBCL including primary CNS lymphoma (106) | 80 (23–174) | 124 (50–216) | 28,521 (545–221,881) |
Hodgkin's lymphoma (32) | 126 (50–276) | 282 (81–391) | 1013 (75–115,562) | ||||
Burkitts lymphoma (29) | 178 (66–230) | 256 (163–401) | 18,230 (2015–97,220) | ||||
High grade B cell non–Hodgkin’s lymphoma (15) | 155 (71–253) | 219 (166–429) | 25,400 (1944–59,871) | ||||
Plasmablastic lymphoma (8) | 143 (63–247) | 136 (100–221) | 54,076 (28,690–144,823) | ||||
DLBCL/Burkitts overlap (3) | |||||||
Primary effusion lymphoma (2) | |||||||
Aggressive T cell non–Hodgkin’s lymphoma (2) | |||||||
Extranodal NK/T cell lymphoma (1) | |||||||
Anaplastic large cell B cell lymphoma (1) | |||||||
Low grade lymphomas | 11 (4.8) | 0 | 0 | Marginal zone lymphoma (6) | 255 (144–302) | 332 (263–500) | 16,611 (460–18,263) |
Follicular lymphoma (2) | |||||||
Mycosis fungoides (2) | |||||||
Chronic lymphocytic leukemia (1) | |||||||
Acute leukemias and myelodysplasia | 8 (3.5) | 0 | 0 | Acute myeloid leukemia (5) | 85 (32–798) | 469 (83–2752) | 75 (75–346,315) |
Acute lymphoblastic leukemia (2) | |||||||
Myelodysplasia (1) | |||||||
Myeloproliferative neoplasms | 3 (1.3) | 0 | 0 | Chronic myelomonocytic leukemia (2) | |||
Chronic myeloid leukemia (1) | |||||||
Dendritic cell neoplasms | 2 (0.9) | 0 | 0 | Blastic plasmacytoid dendritic cell neoplasm (1) | |||
Follicular dendritic cell neoplasm (1) |
Data on median and IQ range for CD4 and VL results provided in categories of neoplasms where more than three patients were identified