Figure 3.
Omit FO-FC difference (purple mesh) neutron scattering length density maps (contoured at 3.0 σ) for the HIV-1 protease catalytic site at pH 6.0 (left) and pH 4.3 (right).A two-proton transfer has occurred; i.e. D1 on Asp25’ has moved to the OH of darunavir and D2 has been transferred to Asp25. D atoms are coloured teal, and H atoms of darunavir are omitted for clarity. Distances are in Å.
