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. Author manuscript; available in PMC: 2016 Jul 14.
Published in final edited form as: J Am Coll Cardiol. 2015 Sep 15;66(11):1209–1220. doi: 10.1016/j.jacc.2015.06.1334

Table 4.

Subgroup analyses based on eGFR categories in subjects not on dialysis

Variables No. of Patients No. of Events Event Rates* Hazard Ratio (95% CI) P-value Test of Interaction
Outcome: Death 0.15
eGFR <45
EES 395 61 21.74 0.71[0.49,1.03] 0.07
CABG 395 83 25.95 Reference
eGFR 45-60
EES 1073 99 14.4 1.01[0.74,1.38] 0.94
CABG 1073 109 13.0 Reference

Outcomes: Myocardial Infarction 0.96
GFR <45
EES 395 26 8.64 1.75[0.86,3.56] 0.12
CABG 395 14 4.73 Reference
GFR 45-60
EES 1073 60 7.56 1.79[1.12,2.84] 0.01
CABG 1073 37 4.5 Reference

Outcome: Stroke 0.20
GFR <45
EES 395 14 4.95 0.71[0.34,1.48] 0.36
CABG 395 20 6.31 Reference
GFR 45-60
EES 1073 18 2.4 0.37[0.20,0.70] 0.002
CABG 1073 43 4.9 Reference

Outcome: Repeat Revascularization 0.58
GFR <45
EES 395 68 22.32 1.69[1.04,2.75] 0.03
CABG 395 32 11.15 Reference
GFR 45-60
EES 1073 200 24.9 1.98[1.51,2.58] <0.0001
CABG 1073 114 14.2 Reference
*

Kaplan-Meier Estimate.

CABG = coronary artery bypass graft surgery; EES = everolimus eluting stent.