Table 4.
Variables | No. of Patients | No. of Events | Event Rates* | Hazard Ratio (95% CI) | P-value | Test of Interaction |
---|---|---|---|---|---|---|
Outcome: Death | 0.15 | |||||
eGFR <45 | ||||||
EES | 395 | 61 | 21.74 | 0.71[0.49,1.03] | 0.07 | |
CABG | 395 | 83 | 25.95 | Reference | ||
eGFR 45-60 | ||||||
EES | 1073 | 99 | 14.4 | 1.01[0.74,1.38] | 0.94 | |
CABG | 1073 | 109 | 13.0 | Reference | ||
Outcomes: Myocardial Infarction | 0.96 | |||||
GFR <45 | ||||||
EES | 395 | 26 | 8.64 | 1.75[0.86,3.56] | 0.12 | |
CABG | 395 | 14 | 4.73 | Reference | ||
GFR 45-60 | ||||||
EES | 1073 | 60 | 7.56 | 1.79[1.12,2.84] | 0.01 | |
CABG | 1073 | 37 | 4.5 | Reference | ||
Outcome: Stroke | 0.20 | |||||
GFR <45 | ||||||
EES | 395 | 14 | 4.95 | 0.71[0.34,1.48] | 0.36 | |
CABG | 395 | 20 | 6.31 | Reference | ||
GFR 45-60 | ||||||
EES | 1073 | 18 | 2.4 | 0.37[0.20,0.70] | 0.002 | |
CABG | 1073 | 43 | 4.9 | Reference | ||
Outcome: Repeat Revascularization | 0.58 | |||||
GFR <45 | ||||||
EES | 395 | 68 | 22.32 | 1.69[1.04,2.75] | 0.03 | |
CABG | 395 | 32 | 11.15 | Reference | ||
GFR 45-60 | ||||||
EES | 1073 | 200 | 24.9 | 1.98[1.51,2.58] | <0.0001 | |
CABG | 1073 | 114 | 14.2 | Reference |
Kaplan-Meier Estimate.
CABG = coronary artery bypass graft surgery; EES = everolimus eluting stent.