Figure 2.

Accuracy of light chain detection by various methods in patients with amyloid light chain (AL) amyloidosis and underlying plasma cell (PC) disorder. Consistent and inconsistent light chain recognition by immunofixation, serum free light chain test, iFISH of bone marrow (BM) PCs, BM immunohistochemistry (IHC) and BM Multi‐parameter flow cytometry compared with light chain restriction detected by IHC of amyloid deposits in κ and λ AL amyloidosis patients (n = 52, A). Light chain or clonality detection in AL amyloidosis cases without IHC identification of κ or λ amyloid deposits based on various methods (n = 9, B).