Table 11. Comparison of ranking for 22 breast cancer genes, based on mimMiner, Tanimoto and their combination.
No. | Gene | mimMinerc | Tanimoto c | Combination c |
---|---|---|---|---|
1 | RAD51a | 1 | 1 | 1 |
2 | BRCA2 a | 2 | 2 | 2 |
3 | BRCA1 a | 3 | 3 | 3 |
4 | PIK3CA a | 4 | 4 | 4 |
5 | TP53b | 13 | 5 | 5 |
6 | RAD54Lb | 9 | 13 | 10 |
7 | ATMb | 15 | 22 | 17 |
8 | BRIP1 | 47 | 63 | 38 |
9 | CHEK2 | 66 | 41 | 62 |
10 | ESR1 | 72 | 73 | 70 |
11 | AKT1 | 96 | 109 | 102 |
12 | BARD1 | 128 | 64 | 108 |
13 | XRCC3 | 199 | 271 | 205 |
14 | CASP8 | 315 | 344 | 318 |
15 | PHB | 650 | 417 | 479 |
16 | TSG101 | 657 | 476 | 511 |
17 | KRAS | 635 | 726 | 629 |
18 | CDH1 | 688 | 701 | 674 |
19 | HMMR | 3661 | 3362 | 3337 |
20 | PPM1D | 5644 | 4328 | 4920 |
21 | RB1CC1 | 5889 | 5619 | 5697 |
22 | NQO2 | 6492 | 6168 | 6151 |
a as seed genes.
b three successfully predicted genes.
c the C = -14 for mimMiner, -17 for Tanimoto and -16 for Combination.