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. 2016 Jul 14;11(7):e0159138. doi: 10.1371/journal.pone.0159138

Fig 6. Evaluation of different normalization procedures.

Fig 6

Normal Q-Q plots, boxplots, density plots and meanSdPlots were used as qualitative measures in order to compare the log intensity distribution of samples output after normalization. (A) Un-normalized log2 data. (B) Subtract by group mean + semi-global normalization. (C) ComBat + semi-global normalization. (D) Global VSN + Combat normalization. (E) Global LOESS + Combat normalization.