Fig 4. Effect of 1 (1, 3 and 10 mg/kg, n = 6, 8 and 6 animals, respectively) in Swiss male mice tested in the forced swim test (FST, upper panel) and elevated plus maze (EPM).
Animals received an injection of vehicle (V, n = 7 animals/group) or 1 and were tested in the EPM 30min later. Immediately after the test they were submitted to the FST for 6 min. Data represents the means+SEM of immobility time in the FST and the % of open arm entries and time spent in these arms of the EPM. *indicates difference from V group (ANOVA followed by the Duncan test, p<0.05).