Table 4. Cox proportional hazards regression analysis for all-cause mortality.
| Variable | Simple | Multiple | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Age | 1.065 | 1.043–1.086 | <0.0001 | 1.035 | 1.009–1.061 | 0.008 |
| Male gender | 0.645 | 0.381–1.092 | 0.103 | |||
| Diabetes | 2.211 | 1.355–3.607 | 0.001 | 2.145 | 1.126–4.087 | 0.020 |
| Hypertension | 2.690 | 1.561–4.634 | <0.0001 | 1.695 | 0.838–3.428 | 0.142 |
| Dyslipidemia | 1.257 | 0.730–2.167 | 0.410 | |||
| Multi-vessel disease | 2.103 | 1.209–3.658 | 0.008 | 1.077 | 0.522–2.220 | 0.841 |
| Killip class 4 | 6.193 | 3.590–10.683 | <0.0001 | 2.517 | 1.113–5.692 | 0.027 |
| Heart rate | 1.017 | 1.008–1.026 | <0.0001 | |||
| LVEF | 0.911 | 0.889–0.935 | <0.0001 | 0.927 | 0.898–0.957 | <0.0001 |
| CI-AKI | 5.085 | 3.055–8.463 | <0.0001 | |||
| HLI | 3.193 | 1.962–5.197 | <0.0001 | |||
| Combined CI-AKI & HLI | 13.407 | 6.793–26.460 | <0.0001 | 6.617 | 2.500–17.515 | <0.0001 |
Abbreviations. CI = confidence interval; CI-AKI = contrast induced acute kidney injury; HLI = hypoxic liver injury; HR = hazard ratio; LVEF = left ventricular ejection fraction; MACCE = major adverse cardiovascular and cerebrovascular event; MI = myocardial infarction; TLR = target lesion revascularization; TVR = target vessel revascularization.