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. 2016 Jul 14;10(7):e0004799. doi: 10.1371/journal.pntd.0004799

Fig 5. Exogenous DIII and stem fragments block the virus-cell membrane fusion process.

Fig 5

(A) Incubation for 1 h of Vero E6 cells with exogenous DIII and stem fragments at 10 and 20 μM, respectively, followed by washing and subsequent inoculation with ANDV. (B) Inhibition of the fusion of ANDV with the plasma membrane by exogenous DIII and stem fragments. The Gc fragments or controls were added during the 5 min low pH incubation step. The statistical evaluation of each data point was performed in relation to the Mock treatment: ***, P < 0.00025; **, P < 0.0025; *, P < 0.025; ns, not significant.